Phosphodiesterase Type 5 Inhibitors For The Treatment of Erectile Dysfunction: Role Of The Patient Preference
نویسندگان
چکیده
منابع مشابه
Phosphodiesterase type 5 inhibitors for erectile dysfunction.
The cyclic nucleotide signalling pathway mediates the smooth-muscle relaxing effects of nitric oxide necessary for normal erectile function. Down-regulation of this pathway is central to the pathophysiology of many forms of erectile dysfunction (ED), which is often associated with other chronic diseases (e.g. hypertension, type 2 diabetes mellitus) and treatments (e.g. certain drugs, radical pr...
متن کاملPreference for and adherence to oral phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction
Sildenafil was the first orally administered phosphodiesterase-5 inhibitor approved for the treatment of erectile dysfunction. Its successful introduction into clinical practice was soon followed by the launch of two other phosphodiesterase-5 inhibitors: vardenafil and tadalafil. The plethora of choices made the question "which PDE-5 inhibitor?" relevant for patients and clinicians. Despite the...
متن کاملUpdate on the Safety of Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction.
INTRODUCTION Phosphodiesterase type 5 inhibitors (PDE5Is) have demonstrated efficacy in the treatment of erectile dysfunction (ED). Although historically found to have limited drug-related adverse events, emerging data have suggested that PDE5Is might be associated with melanoma or recurrence of prostate cancer after radical prostatectomy. AIM To summarize the literature on the safety of PDE5...
متن کاملPhosphodiesterase type 5 (PDE5) inhibitors for the treatment of erectile dysfunction.
IMPORTANCE TO THE FIELD Since sildenafil was introduced 10 years ago, highly selective phosphodiesterase type 5 inhibitors (PDE5i) have changed the medical management of erectile dysfunction (ED). A significant body of research has been devoted to the use of this class of medication for the treatment of ED and has advanced our understanding of erectile physiology. Recently, investigators have n...
متن کاملPhosphodiesterase-5 (PDE5) Inhibitors In the Management of Erectile Dysfunction.
INTRODUCTION Erectile dysfunction (ED) is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.1 According to data from the Massachusetts Male Aging Study, up to 52% of men between the ages of 40 and 70 are affected by ED.2 Based on findings from the 2001–2002 National Health and Nutrition Examination Survey (NHANES), it is estimated that 18...
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ژورنال
عنوان ژورنال: The Journal of Tepecik Education and Research Hospital
سال: 2009
ISSN: 1305-7073
DOI: 10.5222/terh.2009.21470